The maternal relationship between Catherine Casey and her son FS is confirmed by the direct inheritance path of autosomal DNA down to their DNA tested descendant KO.

The segmental (via DNA segment triangulation) and total DNA shared between KO and other confirmed descendants of Daniel Casey/Margaret Donahue is consistent with the expected ranges for their respective relationships. Since KO descends from Daniel Casey/Margaret Donahue through Catherine Casey and her son FS, the presence of significant shared DNA between KO and other known descendants of Daniel Casey/Margaret Donahue validates the generational links along this maternal line.

This supports the conclusion that DNA was passed from MRCA couple Daniel Casey/Margaret Donahue through Catherine Casey to FS, and ultimately to KO, confirming this direct ancestral connection through multiple generations.