The paternal relationship between José Fernando Del Río and his son Ricardo Del Río Garduño is confirmed by the direct inheritance path of autosomal DNA down to their DNA tested descendant JDR.

The segmental (via DNA segment triangulation) and total DNA shared between JDR and other confirmed descendants of Andrea Ramírez is consistent with the expected ranges for their respective relationships. Since JDR descends from Andrea Ramírez through José Fernando Del Río and his son Ricardo Del Río Garduño, the presence of significant shared DNA between JDR and other known descendants of Andrea Ramírez validates the generational links along this paternal line.

This supports the conclusion that DNA was passed from MRCA Andrea Ramírez through José Fernando Del Río to Ricardo Del Río Garduño, and ultimately to JDR, confirming this direct ancestral connection through multiple generations.