The proposed relationship of Margaret Elizabeth Tierney as the mother of James Joseph Tierney Curran and Edwin Russell Curran MD is supported by DNA evidence indicating shared ancestry within the family lines.

Specifically, DNA evidence confirms a distant cousin relationship between GSGHH (a descendant of the Edwin Russell Curran MD ancestral line) and PCD (a descendant of the James Joseph Tierney Curran ancestral line) with a shared segment of 179.83 cM across 6 HIR segments.

This match is consistent with their placement within these shared ancestral branches.